Method of deleting an IgM gene in an isolated rat cell
US9206404B2 · kind B2 · utility
17Cited by
18References
2Claims
0Family size
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Key dates
| Filing date | Dec 3, 2009 |
| Grant date | Dec 8, 2015 |
| Priority date | — |
| Expiry date | Dec 3, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are methods and compositions for genome editing of one or more loci in a rat, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.