Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof

US9211256B2 · kind B2 · utility

Assignee

• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• Morgana M. Trexler · Baltimore, US
• Jenna L. Graham · Columbia, US
• Jennifer L. Breidenich · Atlanta, US
• Jeffrey P. Maranchi · Clarksburg, US
• Julia B. Patrone · Laurel, US
• Marcia W. Patchan · Columbia, US
• Jennifer H. Elisseeff · Baltimore, US
• Xiomara Calderon-Colon · Laurel, US
• Daniel Mulreany · San Francisco, US
• Qiongyu Guo · Lo Wu, CN

Key dates

• Filing date: Nov 14, 2011
• Grant date: Dec 15, 2015
• Expiry date: Jun 21, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a wound healing composition comprising a biocompatible hydrogel membrane wherein the hydrogel membrane has one or more of the following properties: high water content, high transparency, high permeability, high biocompatibility, high tensile strength and an optimal thickness. The invention further provides methods of treating a wound in a subject in need thereof, comprising contacting the wound with a biocompatible cellulose hydrogel membrane of the invention.