Aryl substituted indoles and their use as blockers of sodium channels
US9212139B2 · kind B2 · utility
20Cited by
15References
61Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2011 |
| Grant date | Dec 15, 2015 |
| Priority date | — |
| Expiry date | Jul 26, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to aryl and heteroaryl substituted compounds of Formula (I), and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, R1, and Z1-Z5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.