Preparation of fingolimod and its salts

US9216943B2 · kind B2 · utility

Assignee

• DR. REDDY'S LABORATORIES LIMITED · IN

Inventors

• Srinivas Katkam · Secunderabad, IN
• Rajeswar Reddy Sagyam · Hyderabad, IN
• Raghavendar Rao Morthala · Medak, IN
• Babu Ireni · Nizamabad, IN
• Krishna Vinigari · Mahabubnagar, IN
• Suresh Kumar Ramdoss · Ramanathapuram, IN
• Srinivasulu Rangineni · Mahabubnagar, IN
• Arjunkumar Tummala · Visakhapatnam, IN
• Javed Iqbal · Hyderabad, IN
• Srinivas ORUGANTI · Hyderabad, IN
• Bhaskar KANDAGATLA · Hyderabad, IN

Key dates

• Filing date: Apr 27, 2012
• Grant date: Dec 22, 2015
• Expiry date: Apr 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C215/28
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.