Therapeutic antibodies against ROR-1 protein and methods for use of same
US9217040B2 · kind B2 · utility
28Cited by
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9Claims
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Key dates
| Filing date | Jan 13, 2012 |
| Grant date | Dec 22, 2015 |
| Priority date | — |
| Expiry date | Jan 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutic antibodies having binding specificity for ROR-1 expressed on cancer cells (particularly leukemic and lymphomic cells) and pharmaceutical compositions containing one or more such antibodies for use in treating cancer. Methods for diagnosing such cancers through in vitro detection of binding to ROR-1 protein expressed on putative cancer cells are also provided.
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