Multimeric forms of antimicrobial peptides
US9220264B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 26, 2013 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Nov 26, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4723
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3. The method includes a composition or combination comprising the multimeric antimicrobial peptides and at least one active pharmaceutical ingredient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.