Drug loaded contrast agents: combining diagnosis and therapy
US9220709B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 21, 2007 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Aug 20, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1694
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides an improvement to methods of drug loading of ultrasound contrast agents. Echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof produced by the method of the invention wherein the echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof contain at least 10% more of a drug as compared to (1) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug prior to emulsifying or (2) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug to lyophilized polymer microcapsules, nanocapsules, or mixtures thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.