Bispecific intracellular delivery vehicles
US9220791B2 · kind B2 · utility
6Cited by
21References
19Claims
0Family size
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Key dates
| Filing date | Feb 5, 2014 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Feb 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.