Sterilization of ciprofloxacin composition
US9220796B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2015 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Jul 1, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods of making sterilized ciprofloxacin compositions. In some embodiments, the method includes the steps of: (a) forming an aqueous suspension comprising ciprofloxacin particles; (b) heating the aqueous suspension comprising ciprofloxacin particles at a temperature range of from about 100° C. to about 120° C.; and (c) allowing the aqueous suspension comprising ciprofloxacin particles to cool down. Also described herein are otic formulations containing ciprofloxacin formed by the disclosed methods, and therapeutic use of such otic formulation for providing sustained release of ciprofloxacin into the ear for treating various otic disorders and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.