Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency

US9221759B2 · kind B2 · utility

Assignees

• Rutgers, the State University of New Jersey · US
• New Jersey Institute of Technology · US

Inventors

• Arkady Mustaev · New York, US
• Maxim Kozlov · New York, US
• Salvatore A. E. Marras · Roselle Park, US
• Lev Krasnoperov · North Caldwell, US
• Laura Wirpsza · Ocean City, US
• Shyamala Pillai · Piscataway, US

Key dates

• Filing date: Jan 13, 2011
• Grant date: Dec 29, 2015
• Expiry date: Jul 10, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/582
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel luminescent compositions of matter containing a fluorophore, synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the use of the compositions in various methods of detection. The invention also provides kits containing the compositions and their conjugates for use in the methods of detection.