Patent · US Active

PRMT5 inhibitors and uses thereof

US9221794B2 · kind B2 · utility

40Cited by
28References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 20, 2013
Grant dateDec 29, 2015
Priority date
Expiry dateDec 20, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D407/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.