Patent · US Active

Inhibitors of histone demethylases

US9221801B2 · kind B2 · utility

4Cited by
7References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 28, 2014
Grant dateDec 29, 2015
Priority date
Expiry dateAug 28, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the formIn which Q is selected from —CH═NR12, —W, —CH2NHR13, —CH═O and —CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.