Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer
US9221866B2 · kind B2 · utility
18Cited by
1References
69Claims
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Key dates
| Filing date | Dec 4, 2014 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Dec 4, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.