Methods and DNA constructs for autoregulating transgene silencing
US9222100B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Aug 24, 2010 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Aug 24, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/8286
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides a method to autoregulate expression of a transgene susceptible to sRNA silencing by concomitantly transcribing RNA from DNA of a transgene and RNA from DNA from at least one sRNA silencing pathway gene. An aspect of the invention provides use of a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator. Also disclosed are transgenic cells and organisms having in their genome a recombinant DNA construct that includes DNA of a transgene and DNA of an sRNA silencing regulator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.