Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US9222113B2 · kind B2 · utility
1Cited by
96References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 2013 |
| Grant date | Dec 29, 2015 |
| Priority date | — |
| Expiry date | Jul 8, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides non-naturally occurring microbial organisms comprising 1,4-butanediol (14-BDO) and gamma-butyrolactone (GBL) pathways comprising at least one exogenous nucleic acid encoding a 14-BDO and GBL pathway enzyme expressed in a sufficient amount to produce 14-BDO and GBL. The invention additionally provides methods of using such microbial organisms to produce 14-BDO and GBL.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.