Dosage and administration for preventing cardiotoxicity in treatment with ERBB2-targeted immunoliposomes comprising anthracycline chemotherapeutic agents
US9226966B2 · kind B2 · utility
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Key dates
| Filing date | Jun 6, 2013 |
| Grant date | Jan 5, 2016 |
| Priority date | — |
| Expiry date | Jun 6, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/566
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for determining dosage of HER2-targeted anthracycline-containing immunoliposomes are disclosed, as are methods of treating cancer patients with HER2-positive tumors using dosages so determined. Upon administration, the dosages share the low cardiotoxicity profile of standard dosages of non-immunoliposomal (untargeted), anthracycline-containing liposomes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.