Salt form of a multi-arm polymer-drug conjugate
US9226969B2 · kind B2 · utility
4Cited by
6References
22Claims
0Family size
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Key dates
| Filing date | Nov 18, 2010 |
| Grant date | Jan 5, 2016 |
| Priority date | — |
| Expiry date | Jan 6, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L2203/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Among other aspects, provided herein is a hydrohalide salt of a multi-arm water-soluble polyethylene glycol-drug conjugate, along with related methods of making and using the same. The hydrohalide salt is stably formed, and appears to be more resistant to hydrolytic degradation than the corresponding free base form of the conjugate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.