TNF-α binding proteins

US9226983B2 · kind B2 · utility

Assignee

• Abb Vie Inc. · US

Inventors

• Lorenzo Benatuil · Northborough, US
• Tariq Ghayur · Holliston, US
• Carrie Goodreau · Ludlow, US
• Peter C. Isakson · Southborough, US
• Jochen G. Salfeld · North Grafton, US

Key dates

• Filing date: Apr 6, 2011
• Grant date: Jan 5, 2016
• Expiry date: Nov 8, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-α), e.g., human TNF-α, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.