Intervention medical device and preparation thereof
US9226994B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2011 |
| Grant date | Jan 5, 2016 |
| Priority date | — |
| Expiry date | Jun 13, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/42
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention discloses an interventional medical device and methods of making the same. At least one coating layer is disposed on the outer surface of the interventional medical device and the material of the outmost layer of the coating layer is a sulfonate group-containing polymer. In the present invention, the material of the outmost layer of the interventional medical device is a sulfonate group-containing polymer. The polymer is endowed with a same surface property as that of heparin in addition to appropriate hydrophilicity due to the presence of the sulfonate group. After the interventional medical device is implanted into the human body, a hydrophilic surface is formed on the outer surface of the interventional medical device which is also negatively charged in the body fluid. Therefore, cells can easily adhere and grow on the outer surface thereof as a result of the enhanced cell compatibility. Furthermore, due to a surface property that is the same as that of heparin, the material is provided with excellent anticoagulant properties which inhibit the thrombosis and lower down the incidence rate of post-operational complications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.