Kalman filter based on-off switch for insulin pump

US9227014B2 · kind B2 · utility

Assignees

• The Board of Trustees of the Laland Stanford Junior University · US
• THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION · US
• The Regents of the University of Colorado, a Body Corporate · US
• Rensselaer Polytechnic Institute · US

Inventors

• Bruce A. Buckingham · Palo Alto, US
• B. Wayne Bequette · Albany, US
• Fraser Cameron · Palo Alto, US
• Darrell M. Wilson · Sunnyvale, US
• H. Peter Chase · Denver, US
• Francis J. Doyle, III · Lompoc, US
• Matthew Stenerson · Daly City, US

Key dates

• Filing date: Feb 7, 2014
• Grant date: Jan 5, 2016
• Expiry date: Feb 7, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2230/63
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Techniques for controlling an insulin pump include determining values for parameters selected from a group including a first prediction time horizon, a predicted glucose threshold (Goff) for turning the insulin pump off, a maximum shut off time within a time window, and duration of the time window. A safety rule is determined based on the maximum shut off time within the duration. Glucose readings are collected up to a current time. An expected current glucose value G and glucose temporal rate of change are determined based only on the glucose readings and a Kalman filter configured for noisy glucose readings. A glucose level (Gh1) is predicted for a future time that is the prediction time horizon after the current time. A command is issued to shut off the insulin pump if it is determined both that Gh1 is less than Goff and that the safety rule is satisfied.