Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy

US9227930B2 · kind B2 · utility

Assignees

• Abb Vie Inc. · US
• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Frauke Pohlki · Wiesbaden, DE
• Udo Lange · Ludwigshafen, DE
• Wilhelm Amberg · Ludwigshafen, DE
• Michael Ochse · Wiesbaden, DE
• Berthold Behl · Ludwigshafen, DE
• Charles W. Hutchins · Libertyville, US

Key dates

• Filing date: Jun 27, 2014
• Grant date: Jan 5, 2016
• Expiry date: Jun 27, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to aminoindane derivatives of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminoindane derivatives, and the use of such aminoindane derivatives for therapeutic purposes. The aminoindane derivatives are GlyT1 inhibitors.