Inhibitor compounds of semicarbazide-sensitive amine oxidases

US9227967B2 · kind B2 · utility

Assignee

• PROXIMAGEN, LLC · US

Inventors

• David Michael Evans · Royston, GB
• Allison Carley · London, GB
• Alison Stewart · London, GB
• Michael Higginbottom · London, GB
• Edward Savory · Cambourne, GB
• Iain Simpson · Cambridge, GB
• Marianne Nilsson · Rimbo, SE
• Martin Haraldsson · Täby, SE
• Erik Nordling · Danderyd, SE
• Tobias Koolmeister · Stockholm, SE

Key dates

• Filing date: Mar 14, 2011
• Grant date: Jan 5, 2016
• Expiry date: Mar 14, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds which inhibit SSAO enzyme activity. Also disclosed are pharmaceutical compositions comprising these compounds and the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumor growth.