Patent · US Active

Antiviral phosphonate analogues and process for preparation thereof

US9227990B2 · kind B2 · utility

9Cited by

21References

16Claims

0Family size

Assignee

Cipla Limited · IN

Inventors

Manjinder Singh Phull · Mumbai, IN
Rajendra Narayanrao Kankan · Jamkhed, IN
Dharmaraj Ramachandra Rao · Jamkhed, IN

Key dates

Filing date	Oct 29, 2013
Grant date	Jan 5, 2016
Priority date	—
Expiry date	Oct 29, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention provides a compound of the Formula (I)wherein R is 9-isopropyl-9H-purin-6-amine; 2-amino-9-isopropyl-1H-purin-6(9H)-one; 4-amino-1-isopropyl pyrimidin-2(1H)-one; or 1-isopropyl-5-methylpyrimidine-2,4(1H,3H)-dione, R′ is —CH2OC(O)R″, and R″ is —C(CH3)3 or —CH(CH3)2 including pharmaceutically acceptable salts thereof. The present invention also provides a process for preparing a compound of formula (Ia) and a compound of formula (I) for use in treating a viral infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.