Patent · US Active

Nogo receptor antagonists and methods of increasing neurite outgrowth

US9228015B2 · kind B2 · utility

1Cited by

26References

5Claims

0Family size

Assignee

BIOGEN IDEC MA INC. · US

Inventors

Daniel H.S. Lee · Sudbury, US
Dingyi Wen · Waltham, US
R. Blake Pepinsky · Arlington, US
Jane K. Relton · Belmont, US
Xinzhong Wang · Wayland, US
Alexey A. Lugovskoy · Woburn, US
Werner Meier · Burlington, US
Ellen Garber · Cambridge, US
Laura Silvian · Newton, US
Paul H. Weinreb · Andover, US

Key dates

Filing date	Jan 2, 2014
Grant date	Jan 5, 2016
Priority date	—
Expiry date	Jan 2, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/53
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are Nogo receptor antagonist polynucleotides. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, nucleic acids encoding the same and antagonist polynucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.