Patent · US Active

Human toll-like receptor inhibitors and methods of use thereof

US9228184B2 · kind B2 · utility

8Cited by

7References

28Claims

0Family size

Assignee

DYNAVAX TECHNOLOGIES CORPORATION · US

Inventors

Cristiana Guiducci · Albany, US
Karen L. Fearon · Lafayette, US
Franck Barrat · San Mateo, US

Key dates

Filing date	Mar 15, 2013
Grant date	Jan 5, 2016
Priority date	—
Expiry date	Mar 28, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/344
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.