Method for assaying OGFOD1 activity
US9228224B2 · kind B2 · utility
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16Claims
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Assignee
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Key dates
| Filing date | Feb 10, 2012 |
| Grant date | Jan 5, 2016 |
| Priority date | — |
| Expiry date | Feb 10, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90245
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to assays for monitoring activity of OGFOD1 activity, in particular, to assays for identifying modulators of OGFOD1 activity. The invention also relates to assays to monitor the prolyl hydroxylase activity of OGFOD1 on its substrate, the human ribosomal protein RPS23. The invention also enables the introduction of 3-hydroxyprolyl residues into peptides and proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.