Moisture-activated self-heating analysis device

US9233368B2 · kind B2 · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Haim H. Bau · Swarthmore, US
• Changchun Liu · Sunnyvale, US
• Michael G. Mauk · Wilmington, US
• Robert W. Hart · Salmon Arm, CA
• Xianbo Qiu · Beijing, CN

Key dates

• Filing date: May 22, 2012
• Grant date: Jan 12, 2016
• Expiry date: May 30, 2033

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0481
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Provided are disposable, moisture-activated, self-heating cartridges useful for, e.g., isothermal nucleic acid amplification, incubation, and thermal actuation, and visual fluorescent detection of the amplification products. These devices may be self-contained and do not require any special instruments to operate.