Method of stimulating insulin secretion and/or modulating INS-1 kinase with substituted pyrazinones and/or substituted tetrahydroquinoxalinones

US9233937B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Gerard Botton · Buc, FR
• Eric Valeur · Brétigny-sur-Orge, FR
• Christine Charon · Gometz-le-Châtel, FR
• Micheline Kergoat · Les Ulis, FR
• Samer Elbawab · Les Ulis, FR

Key dates

• Filing date: Jul 22, 2014
• Grant date: Jan 12, 2016
• Expiry date: Jul 22, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Arylpyrazinone derivatives of formula (I),as insulin secretion stimulators, the preparation and use of these pyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.