Arginase inhibitors as therapeutics
US9233985B2 · kind B2 · utility
30Cited by
0References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 19, 2011 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Jun 16, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds according to Formula I are potent inhibitors of Arginase I and II activity:where R1, R2, R3, R4, D, W, X, Y, and Z are defined in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use in treating or preventing a disease or a condition associated with arginase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.