Fed-batch methods for producing adalimumab
US9234032B2 · kind B2 · utility
20Cited by
74References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2014 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Jan 16, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2511/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.