Stem cell differentiation using novel light-responsive hydrogels
US9234171B2 · kind B2 · utility
6Cited by
1References
15Claims
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Assignee
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Key dates
| Filing date | Dec 8, 2011 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Apr 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2537/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This application discloses a light-responsive hydrogel-based platform that can modulate multiple microenvironmental signals to direct the differentiation of human induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) into neuronal cells. The invention provides novel methods for directing differentiation of neural stem cells into neurons useful for treatment of degenerative diseases or disorders, including but not limited to Alzheimer's, Parkinson's, or spinal cord injury (SCI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.