Method for inducing pluripotency in human somatic cells with PRDM14 or NFRKB
US9234180B2 · kind B2 · utility
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Key dates
| Filing date | Jun 2, 2011 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Jun 2, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods of inducing pluripotency in human somatic cells and methods of maintaining pluripotency in human embryonic stem cells (hESCs) are provided, as well as cells and uses of employing such cells. The methods comprise culturing cells in the presence of (i) OCT4 and SOX2; (ii) at least one of KLF4 and c-MYC; and at least one of PRDM14 and NFRKB.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.