Chimeric adenoviruses for use in cancer treatment
US9234185B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 20, 2014 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Aug 20, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10344
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.