Modified FRT recombination site libraries and methods of use
US9234194B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 16, 2010 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Oct 9, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.