Patent · US Active

Method for generating human milk oligosaccharides (HMOs) or precursors thereof

US9234225B2 · kind B2 · utility

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25Claims

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Assignee

GLYCOM A/S · DK

Inventors

Gyula Dekany · Budapest, HU
Elise Champion · Paris, FR
Andreas Schroven · Templin, DE
Markus Hederos · Svedala, SE

Key dates

Filing date	May 14, 2012
Grant date	Jan 12, 2016
Priority date	—
Expiry date	Jul 26, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y302/0114
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A method for generating human milk oligosaccharides (HMOs) or precursors thereof, compounds obtainable by the method, and uses and compositions involving such compounds. The method comprising the steps of a) providing at least one donor selected from the group of compounds of any of formulae 5 to 10, b) providing at least one acceptor from a group of lactose, LNT, LNnT and derivatives thereof, c) providing at least one enzyme comprising a transglycosidase activity and/or a glycosynthase activity, d) preparing a mixture of the at least one donor, at least one acceptor and at least one enzyme provided in steps a), b) and c); and e) incubating the mixture prepared according to step d).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.