Patent · US Active

Simultaneous quantitative multiple primer detection of Clostridium difficile

US9234248B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

Brown University · US

Inventors

Aartik Sarma · Brookline, US
Anubhav Tripathi · Marlborough, US
Leonard A. Mermel · Barrington, US
Aleksey Novikov · Providence, US
Leah Seward · Attleboro, US
Jennifer Fieber · Tucson, US

Key dates

Filing date	Jul 15, 2010
Grant date	Jan 12, 2016
Priority date	—
Expiry date	Sep 8, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/16
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This invention comprises a multiplex-capable oligonucleotide which is capable of hybridizing to at least one of the C. difficile tcdB, tcdC, or cdtB genes, wherein, wherein said primer consists of a sequence selected from the group consisting of SEQ ID NOS: 1 through 9, or a sequence that exhibits no more than one substitution of a base to a sequence selected from the group consisting of SEQ ID NOS: 1 through 9 and method for polymerase chain reaction (PCR) determining of the presence of a toxigenic strain of C. difficile in a biological sample utilizing said probes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.