CXCR4 and ROBO1 expression as markers for autoimmune diabetes
US9234886B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Sep 12, 2013 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Sep 12, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.