3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs
US9238632B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 9, 2013 |
| Grant date | Jan 19, 2016 |
| Priority date | — |
| Expiry date | Apr 9, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/125
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed in the present invention is a 3-cyanoanilinoalkylarylpiperazine derivatives and use thereof in preparing drugs; the 3-cyanoanilinoalkylarylpiperazine derivatives disclosed by the present invention has very useful pharmaceutical properties and good tolerance, especially the use as novel analgesic drugs, novel antidepressants, and novel analgesic and antidepressive drugs. This class of compounds are central analgesics regulating 5-hydroxytrptamine, and also are novel antidepressants regulating 5-hydroxytrptamine. This class of compounds also has less toxic and side effects and a higher safety range. The 3-cyanoanilinoalkylarylpiperazine derivative is a compound shown as formula (III) or free base or salt thereof:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.