Populations of smooth muscle cells of specific embryonic lineages
US9238795B2 · kind B2 · utility
2Cited by
1References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2012 |
| Grant date | Jan 19, 2016 |
| Priority date | — |
| Expiry date | Jun 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to the production of populations of Smooth Muscle Cells (SMCs) of specific embryonic lineages, such as neuroectodermal and mesodermal SMCs. Pluripotent stem cells are cultured in one or more lineage induction media to produce progenitor cells of a defined embryonic lineage, which are then cultured in an SMC induction medium to produce a population of SMCs of the embryonic lineage. Populations of SMCs of defined lineages may be useful, for example, in accurately modelling vascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.