Patent · US Active

Inhibitors of branched-chain-aminotransferase-1 (BCAT1) for the treatment of brain tumors

US9241993B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

Deutsches Krebsforschungszentrum · DE

Inventors

Bernhard Radlwimmer · Heidelberg, DE
Martje Toenjes · Heidelberg, DE
Sebastian Barbus · Heidelberg, DE
Peter Lichter · Heidelberg, DE

Key dates

Filing date	Jan 27, 2012
Grant date	Jan 26, 2016
Priority date	—
Expiry date	Jan 27, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/531
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described is a compound capable of reducing or inhibiting (a) the biological activity of branched-chain-aminotranferase-1 (BCAT1) or (b) the expression of the gene encoding BCAT1 for use in a method of treating a neoplasia. A preferred compound is 1-(aminomethyl) cyclohexaneacetic acid (gabapentin).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.