Patent · US Active

Substituted benzoazepines as toll-like receptor modulators

US9242964B2 · kind B2 · utility

2Cited by

5References

20Claims

0Family size

Assignees

VentiRx Pharmaceuticals, Inc. · US
Array BioPharma, Inc. · US

Inventors

James Jeffry Howbert · Bellevue, US
Gregory Dietsch · Snohomish, US
Robert Hershberg · Seattle, US
Laurence E. Burgess · Boulder, US
George A. Doherty · Libertyville, US
C. Todd Eary · Longmont, US
Robert D. Groneberg · Boulder, US
Zachary Jones · Boulder, US

Key dates

Filing date	Sep 3, 2013
Grant date	Jan 26, 2016
Priority date	—
Expiry date	Sep 3, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.