Heterocyclic-substituted pyridyl compounds useful as kinase inhibitors

US9242975B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Venkatram Reddy Paidi · Bengaluru, IN
• Sreekantha Ratna Kumar · Bengaluru, IN
• Abhisek Banerjee · Narayanpur, IN
• Ramesh Kumar Sistla · Bengaluru, IN
• Satheesh Kesavan Nair · Kanchinakote, IN
• William J. Pitts · Newtown, US
• John Hynes · Washington Crossing, US

Key dates

• Filing date: Jan 11, 2013
• Grant date: Jan 26, 2016
• Expiry date: Jan 11, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the following formula: wherein A is, or; and X is N or C—R7, or an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, are useful as kinase modulators, including IRAK-4 modulation.