Patent · US Active

TGR5 modulators and methods of use thereof

US9243027B2 · kind B2 · utility

4Cited by
13References
17Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 1, 2013
Grant dateJan 26, 2016
Priority date
Expiry dateNov 5, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J41/0061
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to compounds of Formula A:or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulators useful for the treatment of various diseases, including obesity, insulin sensitivity, inflammation, cholestasis, and bile desaturation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.