Osteoarthritis treatment
US9243061B2 · kind B2 · utility
1Cited by
9References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2009 |
| Grant date | Jan 26, 2016 |
| Priority date | — |
| Expiry date | Dec 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA). In accordance with the present invention, an antagonist of GM-CSF can be effective in the treatment of osteoarthritis. An antagonist of GM-CSF includes, but is not limited to, an antibody that is specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.