Method of enhancing miR-185 expression to reduce low density lipoprotein/cholesterol accumulation in a cell
US9243250B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jun 17, 2013 |
| Grant date | Jan 26, 2016 |
| Priority date | — |
| Expiry date | Jun 17, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y205/01021
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method of quantifying miR-185 as a potential biomarker in lipid disorder or cardiovascular diseases in human. The present invention also provides a method of modulating miR-185 in regulating LDL and cholesterol metabolism in cells. The present invention has therapeutic potential in the treatment of cholesterol/LDL related cardiovascular diseases in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.