Compositions and methods for detecting, diagnosing, and treating cancer
US9244075B2 · kind B2 · utility
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7Claims
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Assignee
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Key dates
| Filing date | Aug 8, 2011 |
| Grant date | Jan 26, 2016 |
| Priority date | — |
| Expiry date | Aug 8, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/705
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides compositions and methods useful for diagnosing, treating, and preventing cancer, particularly ovarian cancer and uterine cancer, based on the discovery that the oocyte specific protein, SAS1R (Sperm Acrosomal SLLP1 Receptor), which is a sperm protein receptor, is also expressed in various cancers, including ovarian cancer and uterine cancer. Six SAS1R variants have been previously identified, and they are encompassed by the invention. The present invention further provides antibodies useful for targeting SAS1R expressing cells and for killing such cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.