Production of tissue engineered heart valves
US9248015B2 · kind B2 · utility
2Cited by
18References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 2006 |
| Grant date | Feb 2, 2016 |
| Priority date | — |
| Expiry date | Jan 14, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention is directed to methods for preparing artificial heart valves by preconditioning a matrix seeded with endothelial cells and smooth muscle cells differentiated from isolated progenitor cells. These cell seeded matrices are exposed to fluid conditions that mimic blood flow through the heart to produce tissue engineered heart valves that are analogous to native heart valves.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.