C-3 alkyl and alkenyl modified betulinic acid derivatives
US9249180B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Feb 21, 2014 |
| Grant date | Feb 2, 2016 |
| Priority date | — |
| Expiry date | Jun 29, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J63/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV:a compound of Formula I The compounds are useful for the treatment of HIV and AIDS.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.