Patent · US Active

Use of mycobacterium smegmatis trehalose dimycolate hydrolase

US9249398B2 · kind B2 · utility

0Cited by

0References

18Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Anil Kumar Ojha · Dorpsstraat, US
Yong Yang · 红钢城街道, CN
Peijun ZHANG · Pittsburgh, US

Key dates

Filing date	May 29, 2013
Grant date	Feb 2, 2016
Priority date	—
Expiry date	Aug 2, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/18
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods are disclosed herein for treating an infection with a Mycobacterium infection. Methods are also disclosed for treating a Mycobacterium biofilm. The method include the use of trehalose dimycolate hydrolase, a variant thereof, or a nucleic acid encoding trehalose dimycolate hydrolase or a variant thereof Methods are also disclosed for detecting a Mycobacterium in a sample from a subject. The methods include treating the sample with trehalose dimycolate hydrolase or a variant thereof, and detecting a Mycobacterium nucleic acid in the sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.