Simultaneous high spatial low temporal resolution magnetic resonance (MR) sequence for dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI)

US9251584B2 · kind B2 · utility

Assignee

• KONINIKLIJKE PHILIPS N.V. · NL

Inventors

• Claudia Calcagno-Mani · New York, US
• Stefan E. Fischer · Heidelberg, DE
• Melanie Suzanne Kotys · Shaker Heights, US
• Venkatesh Mani · New York, US
• Philip Robson · Salisbury, GB
• Sarayu Ramachandran · New York, US
• Zahi Fayad · New York, US

Key dates

• Filing date: Mar 26, 2013
• Grant date: Feb 2, 2016
• Expiry date: Mar 26, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/56366
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A dual magnetic resonance imaging method simultaneously acquires a first and a second time series of MR images wherein the temporal resolution of the first time series of images is larger than that of the second time series while the spatial resolution of the first time series of images is smaller than that of the second time series. Accordingly, in the context of DCE-MRI, the first time series can be used to determine the arterial input function (AIF) while the second time series can be used to determine the concentration time course in the tissue of interest, e.g. in a vessel wall. Therefore, both the AIF and the tissue time course can be acquired with their optimal dynamic signal range.